FANCD2P2

Across TCGA patient cohorts, FANCD2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,304 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FANCD2P2-associated GO terms across cancer lineages are Centriole elongation, Positive regulation of centriole elongation, and DNA-templated DNA replication maintenance of fidelity. Each is linked with FANCD2P2 in more than 19 cancer types. Because this analysis shows association rather than direction, both FANCD2P2-to-partner and partner-to-FANCD2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole elongation grouped by FANCD2P2-low versus FANCD2P2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCD2P2→partner) and Y-score (partner→FANCD2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Centriole elongation →	+0.054	+0.204	<.001	.005	2	20
ESCA	Positive regulation of centriole elongation →	+0.048	+0.229	<.001	.004	3	18
STAD	DNA-templated DNA replication maintenance of fidelity →	+0.066	+0.254	<.001	<.001	3	18
STAD	Regulation of centriole replication →	+0.063	+0.227	<.001	<.001	3	18
STAD	Regulation of chromosome organization →	+0.068	+0.255	<.001	<.001	3	17
ESCA	Negative regulation of gene expression, epigenetic →	+0.064	+0.262	.002	.003	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,304 associations by consensus.

Centriole elongation by FANCD2P2 expression — ESCA

Explore this box plot interactively →