FANCD2P2

Across TCGA pan-cancer cohorts, FANCD2P2 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of FANCD2P2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where FANCD2P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FANCD2P2 is over-expressed in tumor.

LUSC, LIHC, and UCEC are the cancer types where FANCD2P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FANCD2P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.150	.001	4	view →
LIHC	All	All	+0.027	.001	3	view →
UCEC	All	All	+0.184	.020	2	view →
BLCA	All	All	+0.105	.038	2	view →
LUAD	All	All	+0.044	.016	2	view →
HNSC	Male	IV	+0.151	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

FANCD2P2–LUSC

Open the LUSC breakdown →