FANCD2P2

Across TCGA pan-cancer cohorts, FANCD2P2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated FANCD2P2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher FANCD2P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FANCD2P2 expression acts as an unfavorable survival marker, although some lineages such as KIRP and BRCA show a favorable association.

MESO, ESCA, and LUAD are the cancer types where FANCD2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	II,III,IV	0.114	0.619	<.001	54	view →
ESCA	DFS	Tertile	All	0.223	0.887	.005	37	view →
LUAD	DFS	Tertile	III,IV	0.491	0.729	.035	37	view →
KIRC	DFS	Quartile	III,IV	0.277	0.548	.012	26	view →
KIRP	DFS	Tertile	III,IV	0.796	0.467	.004	24	view →
OV	OS	Tertile	All	0.806	0.852	.014	22	view →
LIHC	OS	Tertile	All	0.313	0.595	.001	21	view →
BRCA	OS	Tertile	III,IV	0.908	0.789	.009	19	view →
READ	DFS	Median	II,III,IV	0.884	0.743	.011	17	view →
SKCM	DFS	Tertile	II,III,IV	0.662	0.511	.016	13	view →
GBM	DFS	Median	All	0.202	0.357	.023	9	view →
CHOL	DFS	Tertile	II,III,IV	1.000	0.223	.047	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

FANCD2P2–MESO (DFS)

Open the MESO breakdown →