FANCD2OS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FANCD2OS RNA expression is significantly associated with the protein abundance of many other proteins, with 16,131 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FANCD2OS-associated proteins across cancer lineages are RFC2, GMPS, and VRK1. Each is linked with FANCD2OS in more than 6 cancer types. Because this analysis shows association rather than direction, both FANCD2OS-to-partner and partner-to-FANCD2OS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FANCD2OS versus RFC2 in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCD2OS→partner) and Y-score (partner→FANCD2OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRFC2 →+0.522+0.453<.001<.00137
LSCCGMPS →+0.619+0.454<.001<.00136
GBMVRK1 →+0.468+0.349<.001<.00136
LUADRFC1_T506 →+0.953+0.213<.001<.00136
LUADRSF1_S397 →+0.838+0.201<.001<.00136
LUADKIF11_T926 →+0.989+0.330<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,131 associations by consensus.

FANCD2OS vs RFC2 — GBM

Per-sample scatter of FANCD2OS vs RFC2 in GBM (Pearson r = 0.53).

Explore this scatter interactively →

Exploration