FAM9B

Across TCGA cell cohorts, FAM9B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM9B-associated genes across cancer lineages are PLA2G2E and DBX2. Each is linked with FAM9B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM9B-to-partner and partner-to-FAM9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLA2G2E grouped by FAM9B-low versus FAM9B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM9B→partner) and Y-score (partner→FAM9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PLA2G2E →	+0.070	+6.266	<.001	<.001	3	1
LARGE_INTESTINE	DBX2 →	+0.023	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PLA2G2E by FAM9B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →