FAM98C

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM98C protein abundance is significantly associated with the RNA expression of many other genes, with 11,994 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM98C-associated genes across cancer lineages are NCAPG, CEP55, and BUB1B. Each is linked with FAM98C in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM98C-to-partner and partner-to-FAM98C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM98C versus NCAPG in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98C→partner) and Y-score (partner→FAM98C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCANCAPG →-1.187-0.602<.001<.00136
OVCEP55 →-1.079-0.359<.001<.00136
UCECBUB1B →-1.083-0.368<.001<.00136
BRCABLM →-0.809-0.434<.001<.00136
OVHMMR →-1.350-0.447<.001<.00136
UCECRAD51AP1 →-0.784-0.334<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,994 associations by consensus.

FAM98C vs NCAPG — BRCA

Per-sample scatter of FAM98C vs NCAPG in BRCA (Pearson r = -0.41).

Explore this scatter interactively →

Exploration