FAM98C

Across TCGA patient cohorts, FAM98C mutation is significantly associated with the RNA expression of many other genes, with 370 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM98C-associated genes across cancer lineages are DNAJA1P2, CDY5P, and MIR3137. Each is linked with FAM98C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM98C-to-partner and partner-to-FAM98C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJA1P2 grouped by FAM98C-low versus FAM98C-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98C→partner) and Y-score (partner→FAM98C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	DNAJA1P2 →	+0.040	+4.363	.006	.007	3	2
BRCA	CDY5P →	+0.029	+8.055	<.001	.007	3	2
HNSC	MIR3137 →	+0.667	+5.069	<.001	.008	3	2
BLCA	LINC00572 →	+0.054	+4.588	<.001	.008	3	1
BLCA	RN7SL173P →	+0.199	+4.396	<.001	.006	3	1
BRCA	MIR551B →	+0.276	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 370 associations by consensus.

DNAJA1P2 by FAM98C expression — BLCA

Explore this box plot interactively →