FAM98C

Across TCGA patient cohorts, FAM98C mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM98C-associated genes across cancer lineages are GMP, Osteoblast, and MEP. Each is linked with FAM98C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM98C-to-partner and partner-to-FAM98C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by FAM98C-low versus FAM98C-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98C→partner) and Y-score (partner→FAM98C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GMP →	+0.124	+4.069	<.001	.031	3	1
UCEC	Osteoblast →	+0.042	+1.895	.045	.031	3	1
UCEC	MEP →	+0.039	+2.595	.002	.006	2	1
UCEC	Basophils →	+0.210	+2.321	.007	.035	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GMP by FAM98C expression — HNSC

Explore this box plot interactively →