FAM98C

Across TCGA cell cohorts, FAM98C mutation is significantly associated with the mutation status of many other genes, with 1,517 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM98C-associated genes across cancer lineages are MAGEE2, ANXA3, and HUNK. Each is linked with FAM98C in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM98C-to-partner and partner-to-FAM98C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEE2 grouped by FAM98C-low versus FAM98C-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM98C→partner) and Y-score (partner→FAM98C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MAGEE2 →	+5.014	+5.584	.003	.003	1	3
LUNG_NSCLC_LUAD	ANXA3 →	+5.772	+5.772	.002	.002	1	3
LUNG_NSCLC_LUAD	HUNK →	+4.187	+5.000	.008	.008	1	3
BLOOD_Lymphoma	LIG1 →	+6.014	+6.014	.001	.001	1	3
LUNG_SCLC	MYO1G →	+5.066	+4.502	.007	.007	1	3
LUNG_SCLC	NYNRIN →	+5.066	+4.502	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,517 associations by consensus.

MAGEE2 by FAM98C expression — BLOOD_Lymphoma

Explore this box plot interactively →