family with sequence similarity 90 member A25, pseudogeneGenealiases: []
Q-omics provides the consensus-scored FAM90A25P profile across patient tissues and cancer cell-line models. FAM90A25P expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in LGG. Among the 18 cancer types available for tumor–normal comparison, FAM90A25P is differentially expressed in 3, with the highest sampling consensus in BRCA. Additionally, FAM90A25P RNA expression shows 13,374 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight LGG, BRCA, and ACC as cancer lineages where FAM90A25P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FAM90A25P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FAM90A25P survival associations across molecular data types. FAM90A25P RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FAM90A25P RNA expression–survival associations across cancer types. High FAM90A25P expression shows unfavorable associations in LGG, ACC, THYM and KIRC, but favorable associations in BLCA and PAAD. The LGG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LGG as the clearest survival context for FAM90A25P RNA expression.
This table summarizes FAM90A25P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for FAM90A25P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FAM90A25P shows lower tumor expression in BRCA and KICH and higher tumor expression in CHOL. The BRCA box plot shows higher FAM90A25P RNA expression in normal versus tumor tissue (log2 FC = −0.098, t-test p = .001).
This table shows molecular features associated with FAM90A25P in patient tissues and cancer cell lines. In patient samples, FAM90A25P shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
