FAM90A1

Across TCGA cell cohorts, FAM90A1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FAM90A1-associated genes across cancer lineages are TAAR8, OR52N5, and OR56B1. Each is linked with FAM90A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM90A1-to-partner and partner-to-FAM90A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by FAM90A1-low versus FAM90A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM90A1→partner) and Y-score (partner→FAM90A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	2
LUNG_NSCLC_LUAD	OR52N5 →	+0.071	+5.228	.006	.005	3	1
LUNG_NSCLC_LUAD	OR56B1 →	+0.034	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	OR56A5 →	+0.052	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	MS4A13 →	+0.207	+5.228	<.001	.005	3	1
LARGE_INTESTINE	C6orf118 →	+0.175	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TAAR8 by FAM90A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →