FAM90A1

Across TCGA pan-cancer cohorts, FAM90A1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of FAM90A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM90A1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM90A1 is over-expressed in tumor, although a few such as PRAD and KICH show the opposite, repressed pattern.

KIRC, LUAD, and STAD are the cancer types where FAM90A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM90A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.417	<.001	10	view →
LUAD	All	All	+0.541	<.001	7	view →
STAD	All	II,III,IV	+0.483	.008	5	view →
LIHC	All	All	+0.221	<.001	5	view →
CHOL	All	All	+1.164	<.001	4	view →
LUSC	Male	All	+0.793	<.001	4	view →
PRAD	All	All	−0.464	<.001	2	view →
KICH	Female	III,IV	−0.806	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

FAM90A1–KIRC

Open the KIRC breakdown →