FAM8A2P

Across TCGA pan-cancer cohorts, FAM8A2P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated FAM8A2P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher FAM8A2P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM8A2P expression acts as an unfavorable survival marker, although some lineages such as LUSC and MESO show a favorable association.

KICH, CESC, and THCA are the cancer types where FAM8A2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
CESC	DFS	Tertile	III,IV	0.091	0.728	<.001	72	view →
THCA	DFS	Tertile	III,IV	0.485	0.900	<.001	63	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	54	view →
COAD	DFS	Tertile	All	0.325	0.709	<.001	54	view →
STAD	OS	Quartile	IV	0.138	0.502	.009	36	view →
LIHC	DFS	Tertile	II,III,IV	0.257	0.463	.005	33	view →
PCPG	DFS	Tertile	All	0.159	0.830	<.001	33	view →
LUAD	OS	Tertile	All	0.720	0.826	.001	30	view →
LUSC	OS	Tertile	II,III,IV	0.758	0.580	.032	24	view →
ESCA	OS	Tertile	All	0.603	0.735	.036	12	view →
MESO	DFS	Tertile	All	1.000	0.178	.032	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

FAM8A2P–KICH (DFS)

Open the KICH breakdown →