Across TCGA pan-cancer cohorts, FAM8A2P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FAM8A2P’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where FAM8A2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM8A2P is over-expressed in tumor.
UCEC, LUSC, and LUAD are the cancer types where FAM8A2P tumor–normal differential expression is most reproducible.