FAM89B

Across TCGA patient cohorts, FAM89B mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM89B-associated genes across cancer lineages are RN7SL495P, ABHD17AP9, and RN7SL557P. Each is linked with FAM89B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM89B-to-partner and partner-to-FAM89B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL495P grouped by FAM89B-low versus FAM89B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM89B→partner) and Y-score (partner→FAM89B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL495P →	+0.228	+4.750	<.001	.005	3	2
BLCA	ABHD17AP9 →	+0.074	+7.640	<.001	.009	3	1
BLCA	RN7SL557P →	+0.139	+7.640	<.001	.009	3	1
COAD	MIR498 →	+0.306	+7.741	<.001	.009	3	1
COAD	NDUFA5P7 →	+0.174	+7.741	<.001	.009	3	1
UCEC	RNA5SP414 →	+1.098	+3.840	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

RN7SL495P by FAM89B expression — UCEC

Explore this box plot interactively →