FAM87A

Across TCGA patient cohorts, FAM87A mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM87A-associated genes across cancer lineages are RN7SL248P, MIR6780B, and MIR8053. Each is linked with FAM87A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM87A-to-partner and partner-to-FAM87A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by FAM87A-low versus FAM87A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM87A→partner) and Y-score (partner→FAM87A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.139	+4.722	<.001	.004	3	1
UCEC	MIR6780B →	+0.469	+3.889	<.001	.004	3	1
UCEC	MIR8053 →	+0.527	+4.582	<.001	.005	3	1
UCEC	RFPL4AP6 →	+0.203	+3.354	.001	.007	3	1
UCEC	SNORD116-10 →	+0.335	+4.335	<.001	.007	3	1
UCEC	RNU6-674P →	+0.919	+4.286	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

RN7SL248P by FAM87A expression — UCEC

Explore this box plot interactively →