FAM86DP

Across TCGA patient cohorts, FAM86DP mutation is significantly associated with the RNA expression of many other genes, with 1,543 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86DP-associated genes across cancer lineages are CCNHP1, RN7SL654P, and HINT1P2. Each is linked with FAM86DP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86DP-to-partner and partner-to-FAM86DP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNHP1 grouped by FAM86DP-low versus FAM86DP-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86DP→partner) and Y-score (partner→FAM86DP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCNHP1 →	+0.149	+5.600	<.001	<.001	3	2
LUSC	RN7SL654P →	+0.290	+7.327	<.001	<.001	3	2
LUSC	HINT1P2 →	+0.223	+4.984	.001	.009	3	2
COAD	MIR920 →	+0.446	+5.547	<.001	.002	3	2
UCEC	RNU6-222P →	+0.599	+3.001	<.001	<.001	3	2
UCEC	MIR4744 →	+0.383	+2.640	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,543 associations by consensus.

CCNHP1 by FAM86DP expression — HNSC

Explore this box plot interactively →