FAM86DP

Across TCGA pan-cancer cohorts, FAM86DP RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FAM86DP data layer compared with 2 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher FAM86DP RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM86DP expression acts as an unfavorable survival marker, although some lineages such as UVM and OV show a favorable association.

UVM, OV, and LIHC are the cancer types where FAM86DP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.782	0.377	<.001	148	view →
OV	DFS	Median	All	0.606	0.474	<.001	108	view →
LIHC	OS	Median	All	0.408	0.583	<.001	72	view →
ACC	DFS	Median	All	0.498	0.815	<.001	71	view →
KIRC	DFS	Tertile	II,III,IV	0.707	0.919	.002	56	view →
MESO	DFS	Median	III,IV	0.270	0.468	.007	48	view →
LGG	OS	Median	All	0.756	0.867	<.001	41	view →
THYM	DFS	Median	II,III,IV	0.950	0.736	<.001	29	view →
KICH	DFS	Tertile	II,III,IV	0.695	1.000	.010	27	view →
BRCA	OS	Quartile	IV	0.772	0.154	.006	21	view →
BLCA	OS	Tertile	IV	0.472	0.746	.003	19	view →
SARC	OS	Median	All	0.435	0.736	<.001	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FAM86DP–UVM (DFS)

Open the UVM breakdown →