FAM86C2P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM86C2P mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM86C2P-associated genes across cancer lineages are RSL24D1P5, DNM1P5, and RN7SL865P. Each is linked with FAM86C2P in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM86C2P-to-partner and partner-to-FAM86C2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RSL24D1P5 grouped by FAM86C2P-low versus FAM86C2P-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM86C2P→partner) and Y-score (partner→FAM86C2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARSL24D1P5 →+0.089+7.640<.001.00932
BLCADNM1P5 →+0.099+7.640<.001.00932
SKCMRN7SL865P →+0.126+6.810<.001<.00132
SKCMBSN-AS1 →+0.100+4.188.003.00931
COADRNU6-1252P →+0.526+7.741<.001.00931
COADTSPY15P →+0.084+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

RSL24D1P5 by FAM86C2P expression — BLCA

Box plot of RSL24D1P5 in FAM86C2P-low vs FAM86C2P-high samples in BLCA.

Explore this box plot interactively →

Exploration