Q-omics provides the consensus-scored DNM1P5 profile across patient tissues and cancer cell-line models. DNM1P5 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, DNM1P5 RNA expression shows 3,232 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, and STAD as cancer lineages where DNM1P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for DNM1P5 — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes DNM1P5 survival associations across molecular data types. DNM1P5 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DNM1P5 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	MESO (72)	view →

This table ranks reproducible DNM1P5 RNA expression–survival associations across cancer types. High DNM1P5 expression shows unfavorable associations in MESO, BRCA, OV, KIRP and SKCM, but favorable associations in LGG. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for DNM1P5 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.071	0.572	<.001	72	view →
BRCA	DFS	Tertile	III,IV	0.259	0.799	<.001	72	view →
OV	OS	Tertile	II,III,IV	0.355	0.847	.001	54	view →
KIRP	OS	Tertile	II,III,IV	0.176	0.743	.007	36	view →
LGG	DFS	Tertile	All	0.662	0.382	.001	21	view →
SKCM	DFS	Tertile	All	0.058	0.757	<.001	18	view →

Pink = unfavorable, green = favorable. all 10 lineages →

DNM1P5-MESO (OS)

Kaplan–Meier survival curve for DNM1P5 RNA expression in MESO: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DNM1P5 in patient tissues and cancer cell lines. In patient samples, DNM1P5 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	3,232	STAD (2375)	view →
RNA	1,302	STAD (319)	view →