FAM86C2P

Across TCGA pan-cancer cohorts, FAM86C2P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FAM86C2P data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FAM86C2P RNA is associated with better overall survival. In most high-consensus cancer types, elevated FAM86C2P expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

KIRC, STAD, and BRCA are the cancer types where FAM86C2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.697	0.562	<.001	86	view →
STAD	OS	Median	IV	0.288	0.685	<.001	33	view →
BRCA	DFS	Tertile	II,III,IV	0.927	0.863	.003	27	view →
THYM	DFS	Tertile	All	1.000	0.673	.001	26	view →
SARC	DFS	Tertile	All	0.775	0.480	<.001	18	view →
PAAD	DFS	Median	II,III,IV	0.373	0.532	.004	17	view →
OV	DFS	Tertile	III,IV	0.574	0.460	.008	14	view →
LIHC	DFS	Tertile	All	0.369	0.522	.004	14	view →
READ	OS	Median	II,III,IV	0.931	0.688	.014	13	view →
PCPG	OS	Median	All	0.939	1.000	.025	11	view →
BLCA	OS	Median	All	0.484	0.668	.030	10	view →
KIRP	DFS	Tertile	All	0.878	0.561	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FAM86C2P–KIRC (OS)

Open the KIRC breakdown →