FAM83E

Across TCGA patient cohorts, FAM83E protein abundance is significantly associated with the RNA expression of many other genes, with 17,636 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM83E-associated genes across cancer lineages are SPACA4, AGR2, and FUT2. Each is linked with FAM83E in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM83E-to-partner and partner-to-FAM83E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM83E versus SPACA4 in BRCA, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83E→partner) and Y-score (partner→FAM83E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPACA4 →	+1.396	+1.016	<.001	<.001	3	7
UCEC	AGR2 →	+2.681	+1.130	<.001	<.001	3	6
PDAC	FUT2 →	+1.433	+0.829	<.001	<.001	3	6
BRCA	SLC44A4 →	+1.848	+0.866	.004	.003	3	6
LUAD	BCAS1 →	+1.959	+0.810	<.001	<.001	3	6
COAD	ST6GALNAC1 →	+2.788	+0.907	.006	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,636 associations by consensus.

FAM83E vs SPACA4 — BRCA

Explore this scatter interactively →