FAM83E

Across TCGA cell cohorts, FAM83E mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM83E-associated genes across cancer lineages are PATE1, S100G, and KCND3. Each is linked with FAM83E in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM83E-to-partner and partner-to-FAM83E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PATE1 grouped by FAM83E-low versus FAM83E-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM83E→partner) and Y-score (partner→FAM83E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PATE1 →	+0.033	+2.974	<.001	.006	3	1
LARGE_INTESTINE	S100G →	+1.020	+2.688	<.001	.008	3	1
LARGE_INTESTINE	KCND3 →	+0.308	+3.548	.004	.004	3	1
LARGE_INTESTINE	ABCG4 →	+0.305	+3.674	<.001	.001	3	1
LARGE_INTESTINE	PPP3R2 →	+0.037	+2.621	<.001	.008	3	1
LARGE_INTESTINE	CELA2B →	+0.042	+2.688	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

PATE1 by FAM83E expression — OVARY

Explore this box plot interactively →