FAM76A

Across TCGA pan-cancer cohorts, FAM76A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM76A data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM76A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM76A expression acts as an unfavorable survival marker.

LUAD, KIRC, and BLCA are the cancer types where FAM76A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.223	0.812	<.001	27	view →
KIRC	OS	Median	All	0.116	0.811	<.001	18	view →
BLCA	DFS	Median	IV	0.083	0.476	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAM76A–LUAD (OS)

Open the LUAD breakdown →