FAM71E2

Across TCGA patient cohorts, FAM71E2 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71E2-associated genes across cancer lineages are ACC1, PCNA, and STAT3_pY705. Each is linked with FAM71E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71E2-to-partner and partner-to-FAM71E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by FAM71E2-low versus FAM71E2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71E2→partner) and Y-score (partner→FAM71E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.274	+1.289	.018	.023	3	2
COAD	PCNA →	+0.301	+3.178	.013	.010	3	2
UCEC	STAT3_pY705 →	-0.289	-1.289	<.001	.023	3	2
UCEC	Cyclin-B1 →	+0.749	+2.999	<.001	<.001	3	2
COAD	Cyclin-E2 →	+0.300	+2.832	.008	.034	3	2
COAD	Bad_pS112 →	-0.209	-3.161	.031	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

ACC1 by FAM71E2 expression — UCEC

Explore this box plot interactively →