FAM53C

Across TCGA patient cohorts, FAM53C RNA expression is significantly associated with the RNA expression of many other genes, with 19,713 significant associations in total. ACC shows the largest number of these associations.

The most reproducible FAM53C-associated genes across cancer lineages are ZC3H7A, IKZF4, and CCNT1. Each is linked with FAM53C in more than 33 cancer types. Because this analysis shows association rather than direction, both FAM53C-to-partner and partner-to-FAM53C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM53C versus ZC3H7A in DLBC, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM53C→partner) and Y-score (partner→FAM53C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	ZC3H7A →	+1.193	+1.185	<.001	<.001	3	34
DLBC	IKZF4 →	+1.172	+1.165	<.001	<.001	3	34
DLBC	CCNT1 →	+1.128	+1.167	<.001	<.001	3	34
KICH	LARS1 →	+0.965	+0.633	<.001	<.001	3	34
KICH	PUM1 →	+1.089	+1.249	<.001	<.001	3	34
DLBC	REV1 →	+1.242	+1.161	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,713 associations by consensus.

FAM53C vs ZC3H7A — DLBC

Explore this scatter interactively →