FAM50A

Across TCGA patient cohorts, FAM50A protein abundance is significantly associated with the RNA expression of many other genes, with 17,989 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM50A-associated genes across cancer lineages are CENPI, CENPM, and DKC1. Each is linked with FAM50A in more than 8 cancer types. Because this analysis shows association rather than direction, both FAM50A-to-partner and partner-to-FAM50A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM50A versus CENPI in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM50A→partner) and Y-score (partner→FAM50A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPI →	+1.066	+0.377	<.001	<.001	3	9
UCEC	CENPM →	+1.740	+0.307	<.001	<.001	3	8
UCEC	DKC1 →	+0.815	+0.219	<.001	<.001	2	9
GBM	KNL1 →	+1.198	+0.343	<.001	<.001	3	8
LSCC	SASS6 →	+0.586	+0.290	<.001	<.001	3	8
OV	ERCC6L →	+0.798	+0.483	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,989 associations by consensus.

FAM50A vs CENPI — LUAD

Explore this scatter interactively →