FAM50A

Across TCGA cell cohorts, FAM50A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,709 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM50A-associated GO terms across cancer lineages are Positive regulation of microtubule nucleation, Behavioral response to pain, and L-amino acid metabolic process. Each is linked with FAM50A in more than 12 cancer types. Because this analysis shows association rather than direction, both FAM50A-to-partner and partner-to-FAM50A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of microtubule nucleation grouped by FAM50A-low versus FAM50A-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM50A→partner) and Y-score (partner→FAM50A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of microtubule nucleation →	+0.149	+1.232	<.001	.005	3	13
LIVER	Behavioral response to pain →	+0.263	+1.073	<.001	.001	3	11
LARGE_INTESTINE	L-amino acid metabolic process →	-0.088	-1.151	<.001	<.001	3	11
LIVER	Amino acid metabolic process →	-0.082	-1.367	<.001	<.001	3	10
LIVER	Actin filament depolymerization →	+0.183	+1.072	<.001	.007	2	11
BLOOD_Myeloma	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.060	+1.126	.003	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,709 associations by consensus.

Positive regulation of microtubule nucleation by FAM50A expression — SKIN

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