Across TCGA cell cohorts, FAM47C mutation is significantly associated with the RNA expression of many other genes, with 118 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM47C-associated genes across cancer lineages are OR4E2, TGM7, and CCDC70. Each is linked with FAM47C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47C-to-partner and partner-to-FAM47C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47C→partner) and Y-score (partner→FAM47C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR4E2 →	+1.170	+3.874	<.001	.005	3	2
URINARY_TRACT	TGM7 →	+0.013	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUSC	CCDC70 →	+0.039	+3.807	<.001	.003	3	1
BLOOD_Leukemia	H2BW1 →	+0.060	+3.874	.001	.005	3	1
BLOOD_Leukemia	HEPACAM →	+0.586	+3.944	<.001	.006	3	1
BLOOD_Leukemia	OR2Z1 →	+0.035	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 118 associations by consensus.

Exploration

FAM47C survival (RNA) · tumor vs normal (RNA) · all FAM47C data types