Across TCGA cell cohorts, FAM47B mutation is significantly associated with the RNA expression of many other genes, with 410 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM47B-associated genes across cancer lineages are KHDC3L, PRRT1B, and CCNP. Each is linked with FAM47B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47B-to-partner and partner-to-FAM47B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47B→partner) and Y-score (partner→FAM47B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KHDC3L →	+0.024	+2.951	<.001	.003	3	2
SKIN	PRRT1B →	+0.038	+4.054	<.001	.004	3	2
LARGE_INTESTINE	CCNP →	+1.152	+2.628	.001	.002	3	2
LARGE_INTESTINE	PNKD →	+0.443	+3.295	.003	.003	3	2
LARGE_INTESTINE	STOX1 →	+0.893	+2.389	.003	.006	3	2
LARGE_INTESTINE	INO80E →	+0.352	+2.628	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

Exploration

FAM47B survival (RNA) · tumor vs normal (RNA) · all FAM47B data types