FAM27C

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM27C RNA expression is significantly associated with the protein abundance of many other proteins, with 12,198 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM27C-associated proteins across cancer lineages are WIZ, RPRD2, and SAMD1. Each is linked with FAM27C in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM27C-to-partner and partner-to-FAM27C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM27C→partner) and Y-score (partner→FAM27C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWIZ →+0.327+0.403<.001<.00135
HNSCRPRD2 →+0.236+0.202<.001<.00134
GBMSAMD1 →+0.313+0.371<.001<.00134
GBMDNAJC13 →-0.226-0.474<.001<.00134
BRCAPRPF4 →+0.293+0.189<.001<.00134
BRCARBBP5 →+0.217+0.128.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,198 associations by consensus.

Exploration