FAM25C

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM25C RNA expression is significantly associated with the protein abundance of many other proteins, with 6,399 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM25C-associated proteins across cancer lineages are TTC4_S51, UPP1_S61, and USP2_S252. Each is linked with FAM25C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM25C-to-partner and partner-to-FAM25C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM25C versus TTC4_S51 in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM25C→partner) and Y-score (partner→FAM25C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTTC4_S51 →+0.562+1.217<.001.00132
HNSCUPP1_S61 →+0.650+1.322<.001<.00132
HNSCUSP2_S252 →+1.079+1.573.001<.00132
HNSCUSP9X_S2443 →-0.311-1.750<.001<.00132
GBMZNF687_S519 →-0.414-0.112.005.00132
LSCCZNF185_S453 →+0.606+0.313<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,399 associations by consensus.

FAM25C vs TTC4_S51 — HNSC

Per-sample scatter of FAM25C vs TTC4_S51 in HNSC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration