FAM25BP

Across TCGA patient cohorts, FAM25BP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,258 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM25BP-associated GO terms across cancer lineages are Keratinocyte differentiation, Keratinization, and Epidermal cell differentiation. Each is linked with FAM25BP in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM25BP-to-partner and partner-to-FAM25BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte differentiation grouped by FAM25BP-low versus FAM25BP-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM25BP→partner) and Y-score (partner→FAM25BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Keratinocyte differentiation →	+0.090	+1.144	<.001	<.001	3	10
SKCM	Keratinization →	+0.247	+0.225	<.001	<.001	3	10
ESCA	Epidermal cell differentiation →	+0.069	+1.101	<.001	<.001	3	10
SKCM	Establishment of skin barrier →	+0.104	+0.231	<.001	<.001	3	9
SKCM	Peptide cross-linking →	+0.152	+0.226	<.001	<.001	3	8
SKCM	Regulation of antimicrobial humoral response →	+0.166	+0.226	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,258 associations by consensus.

Keratinocyte differentiation by FAM25BP expression — ESCA

Explore this box plot interactively →