FAM25BP

Across TCGA pan-cancer cohorts, FAM25BP RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated FAM25BP data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM25BP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM25BP expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRC show a favorable association.

LUAD, THYM, and KIRP are the cancer types where FAM25BP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.399	0.677	<.001	72	view →
THYM	DFS	Tertile	II,III,IV	0.696	0.945	<.001	48	view →
KIRP	OS	Tertile	All	0.596	0.893	<.001	45	view →
ESCA	DFS	Quartile	III,IV	0.571	0.297	.007	39	view →
BRCA	OS	Tertile	IV	0.270	0.681	.012	36	view →
LGG	DFS	Tertile	All	0.467	0.837	<.001	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
READ	DFS	Tertile	III,IV	0.082	0.749	<.001	27	view →
SKCM	OS	Tertile	All	0.761	0.883	.006	24	view →
MESO	DFS	Tertile	IV	0.109	0.354	.027	24	view →
KIRC	DFS	Tertile	All	1.000	0.798	.028	21	view →
SCLC	DFS	Tertile	All	0.768	0.229	.007	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

FAM25BP–LUAD (DFS)

Open the LUAD breakdown →