FAM25BP

Across TCGA pan-cancer cohorts, FAM25BP RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FAM25BP’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where FAM25BP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM25BP is over-expressed in tumor.

BRCA, LUSC, and BLCA are the cancer types where FAM25BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM25BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.087	.034	4	view →
LUSC	All	All	+0.192	<.001	3	view →
BLCA	Male	III,IV	+0.640	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

FAM25BP–BRCA

Open the BRCA breakdown →