Across TCGA patient cohorts, FAM24B mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM24B-associated genes across cancer lineages are DEFB106B, RN7SKP79, and RNU6-15P. Each is linked with FAM24B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM24B-to-partner and partner-to-FAM24B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM24B→partner) and Y-score (partner→FAM24B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DEFB106B →	+0.073	+5.178	<.001	.002	3	1
HNSC	RN7SKP79 →	+0.121	+4.401	.004	.002	3	1
HNSC	RNU6-15P →	+0.343	+4.787	.001	.001	3	1
HNSC	MIR520G →	+0.223	+4.424	.007	.008	3	1
HNSC	MT-TW →	+0.370	+3.988	.002	.005	3	1
HNSC	SNORD111B →	+0.425	+4.025	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

FAM24B survival (RNA) · tumor vs normal (RNA) · all FAM24B data types