Across TCGA pan-cancer cohorts, FAM24B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FAM24B data layer compared with 1 for mutation status.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FAM24B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM24B expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.
ACC, COAD, and UVM are the cancer types where FAM24B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.