FAM238B

Across TCGA patient cohorts, FAM238B mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM238B-associated genes across cancer lineages are RNU4-56P, RNU6-391P, and MTHFD2P5. Each is linked with FAM238B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM238B-to-partner and partner-to-FAM238B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-56P grouped by FAM238B-low versus FAM238B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM238B→partner) and Y-score (partner→FAM238B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-56P →	+0.348	+4.997	.002	.003	3	1
UCEC	RNU6-391P →	+0.498	+4.442	<.001	.007	3	1
UCEC	MTHFD2P5 →	+0.137	+4.221	.008	.003	3	1
UCEC	ERHP2 →	+0.155	+4.352	.003	.008	3	1
UCEC	RN7SL191P →	+0.249	+4.666	.002	.001	3	1
UCEC	ATP5F1AP7 →	+0.031	+4.267	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

RNU4-56P by FAM238B expression — UCEC

Explore this box plot interactively →