FAM238B

Across TCGA pan-cancer cohorts, FAM238B RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of FAM238B’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where FAM238B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM238B is over-expressed in tumor.

HNSC, LIHC, and STAD are the cancer types where FAM238B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM238B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.094	.015	8	view →
LIHC	All	All	+0.019	.003	4	view →
STAD	Male	II,III,IV	+0.076	.014	3	view →
UCEC	All	All	+0.134	.048	2	view →
KIRC	All	All	+0.011	.024	2	view →
LUAD	All	All	+0.081	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

FAM238B–HNSC

Open the HNSC breakdown →