FAM237A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM237A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM237A-associated genes across cancer lineages are Plasma cells and Osteoblast. Each is linked with FAM237A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM237A-to-partner and partner-to-FAM237A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma cells grouped by FAM237A-low versus FAM237A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM237A→partner) and Y-score (partner→FAM237A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMPlasma cells →+0.032+2.826.008.03631
UCECOsteoblast →-0.047-2.300.038.03631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Plasma cells by FAM237A expression — SKCM

Box plot of Plasma cells in FAM237A-low vs FAM237A-high samples in SKCM.

Explore this box plot interactively →

Exploration