FAM237A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM237A RNA expression is significantly associated with the go_rna of many other GO terms, with 92 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FAM237A-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Protein localization to vacuole, and Canonical Wnt signaling pathway. Each is linked with FAM237A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM237A-to-partner and partner-to-FAM237A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by FAM237A-low versus FAM237A-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM237A→partner) and Y-score (partner→FAM237A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSEnergy derivation by oxidation of organic compounds →+0.054+0.008.004.00632
LUNG_SCLCProtein localization to vacuole →+0.059+0.653<.001.00632
LUNG_SCLCCanonical Wnt signaling pathway →-0.031-0.367.008.00232
CNSNeuron projection organization →+0.072+0.008.004.00631
CNSNegative regulation of striated muscle cell apoptotic process →+0.072+0.008.007.00631
CNSPositive regulation of glucose metabolic process →-0.055-0.008.002.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

Energy derivation by oxidation of organic compounds by FAM237A expression — CNS

Box plot of Energy derivation by oxidation of organic compounds in FAM237A-low vs FAM237A-high samples in CNS.

Explore this box plot interactively →

Exploration