FAM234A

Across TCGA patient cohorts, FAM234A mutation is significantly associated with the RNA expression of many other genes, with 1,206 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM234A-associated genes across cancer lineages are NPAP1L, RNA5SP432, and MIR7-3. Each is linked with FAM234A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM234A-to-partner and partner-to-FAM234A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPAP1L grouped by FAM234A-low versus FAM234A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM234A→partner) and Y-score (partner→FAM234A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NPAP1L →	+0.113	+5.441	<.001	.005	3	2
CESC	RNA5SP432 →	+0.349	+5.539	<.001	.004	3	2
CESC	MIR7-3 →	+0.370	+6.342	<.001	.001	3	2
SKCM	MIR6089 →	+0.195	+4.411	<.001	.005	3	2
UCEC	GPATCH11 →	+0.433	+2.747	.001	<.001	3	2
UCEC	BOLA3 →	+0.378	+2.270	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,206 associations by consensus.

NPAP1L by FAM234A expression — BRCA

Explore this box plot interactively →