FAM230A

Across TCGA cell cohorts, FAM230A mutation is significantly associated with the RNA expression of many other genes, with 222 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM230A-associated genes across cancer lineages are CNTROB, GP1BA, and MYO19. Each is linked with FAM230A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM230A-to-partner and partner-to-FAM230A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNTROB grouped by FAM230A-low versus FAM230A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230A→partner) and Y-score (partner→FAM230A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CNTROB →	+0.701	+3.502	<.001	.001	3	2
LARGE_INTESTINE	GP1BA →	+0.797	+3.169	<.001	.009	3	2
LARGE_INTESTINE	MYO19 →	+0.850	+3.502	<.001	.001	3	2
LARGE_INTESTINE	RNMT →	+0.555	+2.537	.005	.008	3	1
LARGE_INTESTINE	PRSS54 →	+0.019	+2.345	.005	.007	3	1
LARGE_INTESTINE	MCM4 →	+0.949	+3.237	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

CNTROB by FAM230A expression — LARGE_INTESTINE

Explore this box plot interactively →