Across TCGA patient cohorts, FAM224B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,234 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM224B-associated GO terms across cancer lineages are Sequestering of actin monomers, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, and Protoporphyrinogen IX metabolic process. Each is linked with FAM224B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM224B-to-partner and partner-to-FAM224B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM224B→partner) and Y-score (partner→FAM224B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Sequestering of actin monomers →	-0.049	-0.088	<.001	<.001	3	7
SKCM	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.018	+0.020	<.001	.004	2	6
LUSC	Protoporphyrinogen IX metabolic process →	+0.024	+0.118	<.001	<.001	3	5
TGCT	Exit from mitosis →	+0.024	+0.050	<.001	.001	3	4
TGCT	Nucleosome organization →	+0.032	+0.081	.001	.002	2	5
KIRC	Regulation of RNA export from nucleus →	+0.029	+0.029	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,234 associations by consensus.

Exploration

FAM224B survival (RNA) · tumor vs normal (RNA) · all FAM224B data types