FAM224A

Across TCGA patient cohorts, FAM224A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,586 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible FAM224A-associated GO terms across cancer lineages are Actomyosin contractile ring organization, Regulation of mitotic spindle assembly, and Transcription by RNA polymerase III. Each is linked with FAM224A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM224A-to-partner and partner-to-FAM224A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actomyosin contractile ring organization grouped by FAM224A-low versus FAM224A-high in BLCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM224A→partner) and Y-score (partner→FAM224A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Actomyosin contractile ring organization →	+0.048	+0.003	.004	.001	3	3
KIRP	Regulation of mitotic spindle assembly →	+0.030	+0.005	.001	.001	3	2
KIRP	Transcription by RNA polymerase III →	+0.020	+0.006	.007	<.001	3	2
LUAD	Pyridine-containing compound biosynthetic process →	+0.019	+0.004	.004	<.001	3	2
HNSC	Regulation of antibacterial peptide production →	+0.099	+0.002	.001	.001	2	3
BRCA	Intermediate filament organization →	+0.030	+0.004	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,586 associations by consensus.

Actomyosin contractile ring organization by FAM224A expression — BLCA

Explore this box plot interactively →