FAM223A

Across TCGA patient cohorts, FAM223A RNA expression is significantly associated with the protein abundance of many other proteins, with 1,736 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM223A-associated proteins across cancer lineages are ARHGAP32_S892, NEK9_S801, and SUPT16H_S650. Each is linked with FAM223A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM223A-to-partner and partner-to-FAM223A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM223A versus ARHGAP32_S892 in LUAD, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM223A→partner) and Y-score (partner→FAM223A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARHGAP32_S892 →	-0.997	-0.034	.007	<.001	3	2
HNSC	NEK9_S801 →	+0.332	+0.176	.002	.002	3	2
BRCA	SUPT16H_S650 →	+0.644	+0.092	.003	.007	3	2
LUAD	RASIP1_S328 →	+0.619	+0.038	.001	.001	3	2
OV	CLIP2_S18 →	-1.038	-0.068	.002	.004	3	2
GBM	CRACDL_S881 →	-0.933	-0.030	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,736 associations by consensus.

FAM223A vs ARHGAP32_S892 — LUAD

Explore this scatter interactively →