FAM21FP

Across TCGA patient cohorts, FAM21FP mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM21FP-associated genes across cancer lineages are MRPL57P6, RN7SL178P, and MIR3122. Each is linked with FAM21FP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM21FP-to-partner and partner-to-FAM21FP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL57P6 grouped by FAM21FP-low versus FAM21FP-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM21FP→partner) and Y-score (partner→FAM21FP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MRPL57P6 →	+0.199	+7.930	<.001	.008	3	1
UCEC	RN7SL178P →	+0.195	+4.771	.001	.006	3	1
UCEC	MIR3122 →	+0.871	+4.302	.001	.008	3	1
UCEC	IGHV1OR15-6 →	+0.383	+4.903	.002	.002	3	1
SKCM	RN7SL565P →	+0.128	+7.816	<.001	.008	3	1
SKCM	OR51G1 →	+0.044	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MRPL57P6 by FAM21FP expression — LUAD

Explore this box plot interactively →