FAM209B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM209B mutation is significantly associated with the RNA expression of many other genes, with 1,207 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM209B-associated genes across cancer lineages are RNU4-34P, LINC00397, and ACACA. Each is linked with FAM209B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM209B-to-partner and partner-to-FAM209B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM209B→partner) and Y-score (partner→FAM209B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU4-34P →+0.266+5.060<.001.00132
CESCLINC00397 →+0.191+5.269<.001.00132
UCECACACA →+0.587+3.210.006.00932
SKCMKRT125P →+0.076+4.147<.001<.00132
UCECMMS19 →+0.469+3.201.005.00932
UCECWHAMM →+0.781+3.649<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,207 associations by consensus.

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