FAM209A

Across TCGA patient cohorts, FAM209A mutation is significantly associated with the RNA expression of many other genes, with 373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM209A-associated genes across cancer lineages are RNA5SP143, MIR6783, and FTH1P15. Each is linked with FAM209A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM209A-to-partner and partner-to-FAM209A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP143 grouped by FAM209A-low versus FAM209A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM209A→partner) and Y-score (partner→FAM209A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP143 →	+0.255	+7.731	<.001	.009	3	2
SKCM	MIR6783 →	+0.557	+3.024	<.001	.004	3	2
UCEC	FTH1P15 →	+0.839	+3.354	.005	.005	3	2
SKCM	DEFA5 →	+0.290	+4.039	<.001	.009	3	1
SKCM	DEFA6 →	+0.107	+3.242	<.001	.008	3	1
SKCM	RNU6-199P →	+0.302	+3.002	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 373 associations by consensus.

RNA5SP143 by FAM209A expression — BRCA

Explore this box plot interactively →