FAM201B

Across TCGA patient cohorts, FAM201B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,063 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM201B-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgA isotypes, Smoothened signaling pathway, and Inner mitochondrial membrane organization. Each is linked with FAM201B in more than 21 cancer types. Because this analysis shows association rather than direction, both FAM201B-to-partner and partner-to-FAM201B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgA isotypes grouped by FAM201B-low versus FAM201B-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM201B→partner) and Y-score (partner→FAM201B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Positive regulation of isotype switching to IgA isotypes →	+0.051	+0.269	<.001	<.001	3	22
UCS	Smoothened signaling pathway →	+0.045	+0.433	<.001	<.001	3	21
STAD	Inner mitochondrial membrane organization →	+0.044	+0.255	<.001	<.001	3	20
THYM	Protein import into peroxisome matrix →	+0.052	+0.183	<.001	<.001	3	20
TGCT	Smoothened signaling pathway involved in dorsal/ventral neural tube patterning →	+0.069	+0.410	<.001	<.001	3	20
STAD	Microtubule polymerization →	+0.036	+0.197	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,063 associations by consensus.

Positive regulation of isotype switching to IgA isotypes by FAM201B expression — TGCT

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